Baxter 1A0692 - Nitroglycerin, 5% Dextrose Injection, 25 mg/ 250 ml (100 mcg/ml), Liquid Premix Medication in Glass Container, 12/cs (Rx) (Continental US Only, Excluding IN and ND)

Baxter 1A0692 - Nitroglycerin, 5% Dextrose Injection, 25 mg/ 250 ml (100 mcg/ml), Liquid Premix Medication in Glass Container, 12/cs (Rx) (Continental US Only, Excluding IN and ND)

Baxter 1A0692 Nitroglycerin, 5% Dextrose Injection, 25 mg/ 250 ml (100 mcg/ml)

250 ml each 100 ml contains: 10 mg of nitroglycerin (added as diluted nitroglycerin, usp with propyleneglycol), 5 g dextrose hydrous, usp, 0.84 ml alcohol, usp (added as a dissolution aid) and 105 mg citric acid hydrous, usp added as a buffer. Ph 4.0 (3.0 to 5.0). Hypertonic. 428 mosmol/l (calc). Sterile. Single dose container. Dosage: for intravenous use. Use only if vacuum is present and solution is clear. Administration set can affect amount of nitroglycerin delivered to patient. See insert. Rx only.

Nitroglycerin in 5% Dextrose Injection is a sterile, nonpyrogenic solution of nitroglycerin and dextrose in water for injection. The solution is clear and practically colorless. Each 100 mL contains 10 mg, 20 mg, or 40 mg nitroglycerin (added as Diluted Nitroglycerin, USP with propylene glycol); 5 g Dextrose Hydrous, USP; 0.84 mL Alcohol, USP (added as a dissolution aid); and 105 mg Citric Acid Hydrous, USP (added as a buffer). The pH of the solution is adjusted with sodium hydroxide and, if necessary, hydrochloric acid.

Nitroglycerin in 5% Dextrose Injection is indicated for treatment of peri-operative hypertension; for control of heart failure in the setting of acute myocardial infarction; for treatment of angina pectoris in patients who have not responded to sublingual nitroglycerin and -blockers; and for induction of intraoperative hypotension.

Contraindications of Baxter 1A0692 Nitroglycerin

Nitroglycerin in 5% Dextrose Injection is contraindicated in patients who are allergic to it.

In patients with pericardial tamponade, restrictive cardiomyopathy, or constrictive pericarditis, cardiac output is dependent upon venous return. Intravenous nitroglycerin is contraindicated in patients with these conditions.

Nitroglycerin is also contraindicated in patients with increased intracranial pressure.

Do not use Nitroglycerin in 5% Dextrose Injection in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors) such as sildenafil, tadalafil, or vardenafil. Concomitant use can cause severe hypotension, syncope, or myocardial ischemia.

Do not use Nitroglycerin in 5% Dextrose Injection in patients who are taking the soluble guanylate cyclase stimulator riociguat. Concomitant use can cause hypotension.

How Baxter 1A0692 Nitroglycerin Supplied

Nitroglycerin in 5% Dextrose Injection is supplied in glass container as follows: