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Baxter 2B0843 - Dopamine Hydrochloride, 5% Dextrose Injection, USP, 1600 mcg/ ml, 500 ml, Viaflex Plastic Container, Liquid Premix, 12/cs (Rx) (Continental US Only, Excluding IN and ND)
Baxter 2B0843 Dopamine Hydrochloride, 5% Dextrose Injection, USP, 1600 mcg/ ml, 500 ml, Viaflex Plastic Container, Liquid Premix
Dopamine Hydrochloride and 5% Dextrose Injection, USP is a sterile, nonpyrogenic solution of Dopamine Hydrochloride, USP and Dextrose, USP in Water for Injection. Structural formulas are shown below:
Dopamine Hydrochloride and 5% Dextrose Injection, USP is intended for intravenous use only. It contains no antimicrobial agents. The pH is adjusted with hydrochloric acid and is 3.5 (2.5 to 4.5). Approximately 5 mEq/L sodium bisulfite is added as a stabilizer. The solution provides a caloric content of 170 kcal/L. The solution is intended for single use only. When smaller doses are required, the unused portion should be discarded. Composition and osmolarity are given below:
800 mcg/mL Dopamine Hydrochloride and 5% Dextrose Injection, USP provides 800 mcg/mL Dopamine Hydrochloride, USP and 50 g/L Dextrose Hydrous, USP with an osmolarity of 261 mOsmol/L (calc).
1600 mcg/mL Dopamine Hydrochloride and 5% Dextrose Injection, USP provides 1600 mcg/mL Dopamine Hydrochloride, USP and 50 g/L Dextrose Hydrous, USP with an osmolarity of 269 mOsmol/L (calc).
3200 mcg/mL Dopamine Hydrochloride and 5% Dextrose Injection, USP provides 3200 mcg/mL Dopamine Hydrochloride, USP and 50 g/L Dextrose Hydrous, USP with an osmolarity of 286 mOsmol/L (calc).
Dopamine administered intravenously is a myocardial inotropic agent which also may increase mesenteric and renal blood flow plus urinary output.
Dopamine hydrochloride is designated chemically as 3,4-dihydroxyphenethylamine hydrochloride, a white crystalline powder freely soluble in water. Dopamine (also referred to as 3-hydroxytyramine) is a naturally occurring biochemical catecholamine precursor of norepinephrine.
This VIAFLEX Plus plastic container is fabricated from a specially formulated polyvinyl chloride (PL 2207 Plastic). VIAFLEX containers, including VIAFLEX Plus containers, are made of flexible plastic and are for parenteral use. VIAFLEX Plus on the container indicates the presence of a drug additive in a drug vehicle. The amount of water that can permeate from inside the container into the overwrap is insufficient to affect the solution significantly. Solutions in contact with the plastic container can leach out certain of its chemical components in very small amounts within the expiration period, e.g., di-2-ethylhexyl phthalate (DEHP), up to 5 parts per million. However, the safety of the plastic has been confirmed in tests in animals according to USP biological tests for plastic containers as well as by tissue culture toxicity studies.
Baxter 2B0843 Dopamine Hydrochloride Indication and Usage
Dopamine hydrochloride is indicated for the correction of hemodynamic imbalances present in the shock syndrome due to myocardial infarctions, trauma, endotoxic septicemia, open heart surgery, renal failure and chronic cardiac decompensation as in congestive failure.
Where appropriate, restoration of blood volume with a suitable plasma expander or whole blood should be instituted or completed prior to administration of dopamine hydrochloride.
Patients most likely to respond adequately to dopamine hydrochloride are those in whom physiological parameters, such as urine flow, myocardial function and blood pressure have not undergone profound deterioration. Reports indicate that the shorter the time interval between onset of signs and symptoms and initiation of therapy with volume correction and dopamine hydrochloride, the better the prognosis.
Baxter 2B0843 Dopamine Hydrochloride Contraindications
Dopamine hydrochloride should not be used in patients with pheochromocytoma.
Dopamine hydrochloride should not be administered in the presence of uncorrected tachyarrhythmias or ventricular fibrillation.
Solutions containing dextrose may be contraindicated in patients with known allergy to corn or corn products.
Baxter #2B0833, Dopamine Hydrochloride, 5% Dextrose Injection, USP, 800 mcg/ ml, 500 ml, Viaflex Plastic Container, Liquid Premix, 12/cs (Rx) (Continental US Only, Excluding IN and ND)
$385.65 per CASE
Baxter #2B0842, Dopamine Hydrochloride, 5% Dextrose Injection, USP, 1600 mcg/ ml, 250 ml, Viaflex Plastic Container, Liquid Premix, 18/cs (Rx) (Continental US Only, Excluding IN and ND)
$451.92 per CASE
Baxter #2B0846, Dopamine Hydrochloride, 5% Dextrose Injection, USP, 3200 mcg/ ml, 250 ml, Viaflex Plastic Container, Liquid Premix, 18/cs (Rx) (Continental US Only, Excluding IN and ND)
$629.60 per CASE
Baxter #2B0832, Dopamine Hydrochloride, 5% Dextrose Injection, USP, 800 mcg/ ml, 250 ml, Viaflex Plastic Container, Liquid Premix, 18/cs (Rx) (Continental US Only, Excluding IN and ND)
$370.56 per CASE