BD 231314 - BBL Sensi-Disc Novobiocin NB-5 Susceptibility Test Disc, 10 Each / Pkg
The BD BBL 231314 Sensi-Disc Novobiocin NB-5 is a susceptibility test disc used in microbiology laboratories to determine the susceptibility of bacterial strains, particularly Staphylococcus saprophyticus, to novobiocin. This disc helps in distinguishing between resistant and susceptible bacterial strains, playing a vital role in diagnostic microbiology.
Product Overview and Design Features
The BD BBL 231314 Sensi-Disc is designed as a small paper disc impregnated with 5 g of novobiocin. Key features include:
- Consistent Antibiotic Dosage: Each disc contains a precise amount (5 g) of novobiocin, ensuring consistent and reliable test results.
- Standardized Diameter: The disc has a standardized diameter that fits into most commonly used agar plate diffusion methods.
- Easy Handling: It is lightweight and easy to use, requiring minimal manual handling, reducing the risk of contamination.
- Clear Marking: The disc is clearly labeled with the antibiotic code (NB-5), making it easy for lab personnel to identify and place during testing.
Intended Use in Medical Settings
The primary use of the BD BBL Sensi-Disc is to conduct antimicrobial susceptibility testing (AST), particularly focusing on the identification of novobiocin-resistant bacteria. This is especially useful for differentiating Staphylococcus saprophyticus from other coagulase-negative staphylococci.
In clinical microbiology, the disc is applied as part of a Kirby-Bauer disk diffusion method on an agar plate. After incubation, the zone of inhibition around the disc is measured to determine if the tested bacteria are susceptible or resistant to novobiocin.
Benefits for healthcare professionals:
- Accurate Identification: The Sensi-Disc is a key tool for determining bacterial resistance, aiding in accurate diagnosis and treatment planning.
- Time-Saving: The use of susceptibility discs in diagnostic labs reduces the time needed to identify bacterial resistance compared to more complex testing methods.
- Cost-Effective: These discs are relatively low-cost and efficient for regular use in laboratories.
Certifications, Safety Standards, and Regulatory Approvals
The BD BBL Sensi-Disc meets several regulatory and industry standards:
- CLSI Standards: The product complies with Clinical and Laboratory Standards Institute (CLSI) guidelines for antimicrobial susceptibility testing.
- ISO Certification: The production process adheres to ISO 9001 standards, ensuring high manufacturing quality and consistency.
- FDA Clearance: In the U.S., the product is cleared for use in clinical laboratories by the FDA.
These certifications assure laboratories and healthcare providers that the product meets stringent safety, accuracy, and performance standards.
Comparison with Other Products
The BD BBL Novobiocin Sensi-Disc has several competitors on the market, including discs from Oxoid and Thermo Fisher Scientific. Here is a comparison table highlighting the key differences:
| Feature | BD BBL 231314 | Oxoid Novobiocin Disc | Thermo Fisher Novobiocin Disc |
|---|---|---|---|
| Antibiotic Content | 5 g Novobiocin | 5 g Novobiocin | 5 g Novobiocin |
| Diameter | Standard (6 mm) | Standard (6 mm) | Standard (6 mm) |
| Regulatory Approvals | FDA, ISO, CLSI | FDA, ISO | FDA, ISO |
| Price Point | Moderate | Low | Moderate |
| Compatibility with Kirby-Bauer | Fully Compatible | Fully Compatible | Fully Compatible |
| Packaging | Bulk (box of 50 or 100 discs) | Box of 50 discs | Box of 100 discs |
| Marking on Disc | Clear NB-5 label | NB-5 label | NB-5 label |
Unique Features:
- Precise Dosing and Marking: The BD BBL disc is known for its high manufacturing standards, particularly its precise novobiocin content and clear labeling, reducing the risk of error during the setup of susceptibility tests.
- Durability: The BD Sensi-Disc is designed to maintain stability even during long storage periods, ensuring consistent performance over time.
Common User Profile and Typical Scenarios
The BD BBL Sensi-Disc is primarily used by:
- Microbiologists and Lab Technicians: It is a standard tool in microbiology labs, used by professionals conducting routine susceptibility testing.
- Healthcare Providers in Hospitals: Hospitals rely on susceptibility testing results to make informed decisions on antibiotic therapy for infections.
- Clinical Research Facilities: Researchers working on antimicrobial resistance studies use these discs to track and document bacterial resistance patterns.
Typical scenarios include:
- Urinary Tract Infections (UTIs): Testing for novobiocin susceptibility is crucial in distinguishing Staphylococcus saprophyticus, a common UTI pathogen.
- Hospital-Acquired Infections: Differentiating between coagulase-negative staphylococci strains helps guide appropriate antibiotic treatment in hospital settings.
Best Practices for Using and Maintaining the Product
To ensure safety and accuracy when using the BD BBL Sensi-Disc:
- Proper Storage: Store the discs in a cool, dry environment at 2-8 Degree Celsius to maintain potency. Avoid exposure to heat or moisture.
- Aseptic Handling: Always use sterilized forceps or a disc dispenser to handle the discs, avoiding direct contact with hands to prevent contamination.
- Timely Use: Ensure the discs are used within their expiration date for optimal results. Expired discs may lead to inaccurate susceptibility readings.
- Calibration of Zone Measurement Tools: Regularly calibrate rulers or zone measuring devices used to assess the zone of inhibition to ensure accuracy in results.
By following these best practices, healthcare professionals can ensure consistent and reliable results when using the BD BBL Sensi-Disc Novobiocin NB-5 in clinical settings.
